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Robert Klamroth Selected Research

Hemophilia A (Haemophilia)

4/2024Three-year outcomes of valoctocogene roxaparvovec gene therapy for hemophilia A.
3/2024Benefits and risks of non-factor therapies: Redefining haemophilia treatment goals in the era of new technologies.
2/2024Measurement of recombinant porcine factor VIII in patients with congenital haemophilia A and inhibitors in the presence of emicizumab.
12/2023Emicizumab for the Treatment of Acquired Hemophilia A: Consensus Recommendations from the GTH-AHA Working Group.
12/2023Health-related quality of life following valoctocogene roxaparvovec gene therapy for severe hemophilia A in the phase 3 trial GENEr8-1.
11/2023Emicizumab prophylaxis in patients with acquired haemophilia A (GTH-AHA-EMI): an open-label, single-arm, multicentre, phase 2 study.
10/2023Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study.
9/2023Evaluation of collagen turnover biomarkers as an objective measure for efficacy of treatment with rurioctocog alfa pegol in patients with hemophilia A: a secondary analysis of a randomized controlled trial.
7/2023Matching-adjusted indirect comparison of bleeding outcomes in severe haemophilia A: Comparing valoctocogene roxaparvovec gene therapy, emicizumab prophylaxis, and FVIII replacement prophylaxis.
5/2023Fitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B): a multicentre, open-label, randomised, phase 3 trial.
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Robert Klamroth Research Topics

Disease

46Hemophilia A (Haemophilia)
04/2024 - 04/2009
37Hemorrhage
04/2024 - 01/2007
9Thrombosis (Thrombus)
06/2023 - 03/2008
8Hemophilia B (Haemophilia B)
10/2023 - 09/2012
6Thrombocytopenia (Thrombopenia)
04/2024 - 01/2007
5Venous Thrombosis (Deep-Vein Thrombosis)
04/2024 - 01/2022
5Pulmonary Embolism
04/2024 - 11/2023
5COVID-19
11/2023 - 06/2020
4Venous Thromboembolism
04/2024 - 01/2019
4Neoplasms (Cancer)
03/2024 - 01/2019
3Body Weight (Weight, Body)
01/2023 - 01/2007
3Thrombotic Microangiopathies
11/2022 - 12/2020
3von Willebrand Diseases (von Willebrand's Disease)
05/2014 - 01/2007
2Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune)
01/2023 - 06/2021
2Thrombophilia
01/2013 - 08/2012
1Pulmonary Hypertension
03/2024
1Heart Arrest (Cardiac Arrest)
11/2023
1Intracranial Thrombosis (Cerebral Thrombosis)
06/2023
1Atrial Fibrillation
06/2023
1Gastroenteritis
05/2023
1Asthma (Bronchial Asthma)
05/2023
1Respiratory Tract Infections (Respiratory Tract Infection)
05/2023
1Pneumonia (Pneumonitis)
05/2023
1Cholelithiasis
05/2023
1Osteoarthritis
05/2023
1Diplopia (Double Vision)
05/2023
1Humeral Fractures
05/2023
1Hypertension (High Blood Pressure)
05/2023
1Cholecystitis
05/2023
1Synovitis
03/2023
1acquired Thrombotic thrombocytopenic purpura
01/2023
1Pain (Aches)
01/2023
1Autoimmune Hemolytic Anemia (Cold Agglutinin Disease)
01/2023
1Craniocerebral Trauma (Head Injury)
11/2022
1Myocardial Infarction
11/2022
1Intra-Abdominal Hypertension
11/2022
1Multiple Trauma (Multiple Injuries)
11/2022
1Hematoma
06/2021
1Metrorrhagia (Spotting)
05/2021

Drug/Important Bio-Agent (IBA)

31Factor VIII (Coagulation Factor VIII)IBA
04/2024 - 04/2009
12emicizumabIBA
03/2024 - 08/2017
8Blood Coagulation Factors (Coagulation Factor)IBA
03/2024 - 01/2007
8AnticoagulantsIBA
03/2024 - 08/2012
7Factor IX (Coagulation Factor IX)FDA LinkGeneric
10/2023 - 09/2012
6AutoantibodiesIBA
12/2023 - 04/2009
5Heparin (Liquaemin)FDA LinkGeneric
04/2024 - 03/2008
5Hemostatics (Antihemorrhagics)IBA
02/2022 - 02/2015
4BAX 855IBA
09/2023 - 01/2019
4AntithrombinsIBA
05/2023 - 05/2005
4AntibodiesIBA
03/2022 - 05/2005
4recombinant factor VIII N8IBA
02/2022 - 01/2020
4Proteins (Proteins, Gene)FDA Link
01/2021 - 08/2012
3Valoctocogene RoxaparvovecIBA
04/2024 - 07/2023
3BAY 94-9027IBA
01/2023 - 01/2019
3VaccinesIBA
06/2021 - 06/2021
3Prothrombin (Factor II)IBA
05/2021 - 05/2005
2fitusiranIBA
03/2024 - 05/2023
2Vitamin KFDA Link
03/2024 - 01/2019
2Neutralizing AntibodiesIBA
01/2023 - 09/2013
2Immunoglobulin G (IgG)IBA
01/2023 - 08/2017
2factor IX Fc fusion proteinIBA
01/2021 - 04/2019
2AlbuminsIBA
01/2021 - 09/2012
2factor VIII-Fc fusion proteinIBA
01/2021 - 01/2016
26-pyruvoyltetrahydropterin synthase (PTPS)IBA
01/2020 - 01/2019
2Serum AlbuminIBA
01/2019 - 05/2013
2Factor IXa (Coagulation Factor IXa)IBA
01/2019 - 08/2017
2Fondaparinux (Arixtra)FDA Link
11/2017 - 07/2014
2von Willebrand FactorIBA
08/2013 - 08/2013
2Protein CIBA
08/2012 - 05/2005
2Protein SIBA
08/2012 - 05/2005
1Chromogenic CompoundsIBA
04/2024
1marstacimabIBA
03/2024
1SerpinsIBA
03/2024
1Factor VIIIaIBA
03/2024
1concizumabIBA
03/2024
1Factor Xa InhibitorsIBA
03/2024
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
03/2024
1A-factor (Streptomyces)IBA
11/2023
1CollagenIBA
09/2023
1Biomarkers (Surrogate Marker)IBA
09/2023
1Alanine Transaminase (SGPT)IBA
05/2023
1Small Interfering RNA (siRNA)IBA
05/2023
1Complement System Proteins (Complement)IBA
01/2023
1Inosine Triphosphate (ITP)IBA
01/2023
1insulin receptor-related receptor (IRR)IBA
01/2023
1TESIBA
11/2022
1COVID-19 VaccinesIBA
06/2021
1ChAdOx1 nCoV-19IBA
06/2021
1Indicators and Reagents (Reagents)IBA
01/2021
1prothrombin complex concentrates (PPSB)IBA
01/2020

Therapy/Procedure

18Therapeutics
04/2024 - 01/2007
2Secondary Prevention
11/2023 - 01/2022
2Intravenous Injections
12/2022 - 08/2017
2Injections
05/2019 - 01/2007
1Aftercare (After-Treatment)
01/2023
1Subcutaneous Injections
12/2022
1Tooth Extraction (Tooth Extractions)
11/2022
1Radiotherapy
01/2022
1Intramuscular Injections
06/2021
1Blood Transfusion (Blood Transfusions)
01/2021